Article
Power and precision of alternate methods for linkage disequilibrium mapping of quantitative trait loci.
Genetics - 1 Apr 2007
Zhao H H, Fernando R L, Dekkers J C M
Abstract excerpt
Linkage disequilibrium (LD) analysis in outbred populations uses historical recombinations to detect and fine map quantitative trait loci (QTL). Our objective was to evaluate the effect of various factors on power and precision of QTL detection and to compare LD mapping methods on the basis of regression and identity by descent (IBD) in populations of limited effective population size (N(e)). An 11-cM region with...
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