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Article

The Impact of Selection at the Amino Acid Level on the Usage of Synonymous Codons.

G3 (Bethesda, Md.) - 10 Mar 2017

Błażej Paweł, Mackiewicz Dorota, Wnętrzak Małgorzata, Mackiewicz Paweł

Abstract excerpt

There are two main forces that affect usage of synonymous codons: directional mutational pressure and selection. The effectiveness of protein translation is usually considered as the main selectional factor. However, biased codon usage can also be a byproduct of a general selection at the amino acid level interacting with nucleotide replacements. To evaluate the validity and strength of such an effect, we...

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Identifiers

PMID: 28122952
DOI: 10.1534/g3.116.038125
PMCID: PMC5345726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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