The Impact of Selection at the Amino Acid Level on the Usage of Synonymous Codons.

doi:10.1534/g3.116.038125

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Article

The Impact of Selection at the Amino Acid Level on the Usage of Synonymous Codons.

G3 (Bethesda, Md.) - 10 Mar 2017

Błażej Paweł, Mackiewicz Dorota, Wnętrzak Małgorzata, Mackiewicz Paweł

Abstract excerpt

There are two main forces that affect usage of synonymous codons: directional mutational pressure and selection. The effectiveness of protein translation is usually considered as the main selectional factor. However, biased codon usage can also be a byproduct of a general selection at the amino a...

Topics

Amino Acids
Codon
Models, Genetic
Mutation
Nucleotides
Open Reading Frames
Probability
Selection, Genetic

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