Article
A new locus on chromosome 19 linked with late-onset Alzheimer's disease.
Neuroreport - 4 Dec 2001
Poduslo S E, Yin X
Abstract excerpt
Alzheimer's disease (AD) is a complex neurodegenerative disorder, characterized by cognitive decline and distinctive neuropathology. APOE 4 and APOCI A on chromosome 19 are risk factors for late-onset disease. Using large extended families with multiple siblings affected, we have identified several microsatellite markers which are also linked with late- onset Alzheimer's disease. These microsatellites are distal...
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