Article
Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs.
BMC medical genetics - 1 Dec 2009
Blom Elin S, Giedraitis Vilmantas, Arepalli Sampath, Hamshere Marian L, Adighibe Omanma, Goate Alison, Williams Julie, Lannfelt Lars, Hardy John, Vrièze Fabienne Wavrant-De, Glaser Anna
Abstract excerpt
BACKGROUND: Genome-wide linkage studies for Alzheimer's disease have implicated several chromosomal regions as potential loci for susceptibility genes. METHODS: In the present study, we have combined a selection of affected relative pairs (ARPs) from the UK and the USA included in a previous linkage study by Myers et al. (Am J Med Genet, 2002), with ARPs from Sweden and Washington University. In this total sample...
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