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Article

Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2.

American journal of human genetics - 1 Sept 2004

Wijsman Ellen M, Daw E Warwick, Yu Change-En, Payami Haydeh, Steinbart Ellen J, Nochlin David, Conlon Erin M, Bird Thomas D, Schellenberg Gerard D

Abstract excerpt

Late-onset familial Alzheimer disease (LOFAD) is a genetically heterogeneous and complex disease for which only one locus, APOE, has been definitively identified. Difficulties in identifying additional loci are likely to stem from inadequate linkage analysis methods. Nonparametric methods suffer from low power because of limited use of the data, and traditional parametric methods suffer from limitations in the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 15248153
DOI: 10.1086/423393
PMCID: PMC1182019

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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