Article
Recent advances in the genetics of Alzheimer's disease.
Journal of geriatric psychiatry and neurology - 1 Jan 1998
Levy-Lahad E, Tsuang D, Bird T D
Abstract excerpt
Alzheimer's disease (AD) is a neurodegenerative disorder that is the most common cause of dementia in the elderly. It is a clinical-pathologic entity characterized by progressive dementia associated with the neuropathologic hallmarks of Abeta amyloid plaques, neurofibrillary tangles (NFTs), neuro...
Topics
- Aged
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Apolipoprotein E4
- Apolipoproteins E
- Chromosomal Proteins, Non-Histone
- Chromosome Mapping
- DNA Mutational Analysis
- Genetic Predisposition to Disease
- Humans
- Membrane Proteins
- Presenilin-2
- Risk