Article
PrP genotype in Sarda breed sheep and its relevance to scrapie. Brief report.
Archives of virology - 1 Oct 2001
Vaccari G, Petraroli R, Agrimi U, Eleni C, Perfetti M G, Di Bari M A, Morelli L, Ligios C, Busani L, Nonno R, Di Guardo G
Abstract excerpt
Several PrP gene polymorphisms modulate sheep scrapie susceptibility. Recently, an increase of scrapie outbreaks has been reported in Italy. A vaccine containing sheep brain homogenate was used in most of the outbreaks. We investigated PrP gene polymorphisms in scrapie-affected and clinically healthy Sarda breed sheep from a flock exposed to the aforementioned vaccine, and in affected Sarda sheep from unexposed...
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