Article
Frequency of genotypes in the PrP prion protein gene locus in the Polish sheep population.
Acta veterinaria Hungarica - 1 Mar 2009
Rejduch Barbara, Knapik Jan, Piestrzyńska-Kajtoch Agata, Kozubska-Sobocińska Anna, Krupiński Jedrzej
Abstract excerpt
Scrapie is an invariably fatal transmissible neurodegenerative disease of sheep, goats and moufflons, characterised by ataxia, lower body weight and changes in behaviour. The aim of this study was to determine the genotype distribution at codons 136, 154 and 171 of the PrP locus in sheep bred in Poland. The genotypes of 801 sheep representing 10 different breeds and crossbreds were analysed using real-time PCR...
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