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Article

PrP gene polymorphism and natural scrapie in Icelandic sheep.

The Journal of general virology - 1 Sept 1999

Thorgeirsdottir Stefania, Sigurdarson Sigurdur, Thorisson Hjalti Mar, Georgsson Gudmundur, Palsdottir Astridur

Abstract excerpt

The association between scrapie and polymorphism of the prion protein (PrP) gene was studied in the Icelandic sheep breed. Polymorphism of the three codons, 136, 154 and 171, that are important for scrapie susceptibility was determined. A BspHI restriction analysis was used to study the alleles of codons 136 and 154, while density gradient gel electrophoresis (DGGE) was used to analyse codon 171 and detect new...

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Identifiers

PMID: 10501510
DOI: 10.1099/0022-1317-80-9-2527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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