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Article

DNA adducts, genetic polymorphisms, and K-ras mutation in human pancreatic cancer.

Mutation research - 15 Jan 2002

Li Donghui, Firozi Pervez F, Zhang Weiqing, Shen Jianjun, DiGiovanni John, Lau Serrine, Evans Douglas, Friess Helmut, Hassan Manal, Abbruzzese James L

Abstract excerpt

To test the hypothesis that carcinogen exposure and oxidative stress are involved in pancreatic carcinogenesis in susceptible individuals, aromatic DNA adducts and 8-hydroxyguanosine (8-OH-dG) were measured by (32)P-postlabeling and HPLC-EC, respectively, in 31 pancreatic tumors and 13 normal tissues adjacent to the tumor from patients with pancreatic cancer. Normal pancreatic tissues from 24 organ donors, from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11719088
DOI: 10.1016/s1383-5718(01)00291-1

Genes

GSTM1
NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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