Article
DNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancer.
Molecular carcinogenesis - 1 Jun 2012
Dong Xiaoqun, Li Yanan, Chang Ping, Hess Kenneth R, Abbruzzese James L, Li Donghui
Abstract excerpt
DNA repair plays a critical role in human cancers. We hypothesized that DNA mismatch repair gene variants are associated with risk of pancreatic cancer. We retrospectively genotyped 102 single-nucleotide polymorphisms (SNPs) of 13 mismatch repair related genes in 706 patients with pancreatic cancer and 706 cancer-free controls using the mass spectroscopy-based MassArray method. Association of genotype with...
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