Article
Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk. The International Pancreatic Disease Study Group.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 1998
Bartsch H, Malaveille C, Lowenfels A B, Maisonneuve P, Hautefeuille A, Boyle P
Abstract excerpt
Carcinogens present in cigarette smoke and diet have been associated with pancreatic cancer. We hypothesized that heterocyclic and aromatic amines implicated in these exposures could be involved as causative agents and that therefore genetic variation in enzymes metabolizing these carcinogens cou...
Topics
- Acetyltransferases
- Adult
- Aged
- Arylamine N-Acetyltransferase
- Case-Control Studies
- DNA
- Female
- Genotype
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)