Article
Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21.
Genomics - 1 Nov 2001
Olivier M, Bustos V I, Levy M R, Smick G A, Moreno I, Bushard J M, Almendras A A, Sheppard K, Zierten D L, Aggarwal A, Carlson C S, Foster B D, Vo N, Kelly L, Liu X, Cox D R
Abstract excerpt
One approach to identify potentially important segments of the human genome is to search for DNA regions with nonrandom patterns of human sequence variation. Previous studies have investigated these patterns primarily in and around candidate gene regions. Here, we determined patterns of DNA sequence variation in 2.5 Mb of finished sequence from five regions on human chromosome 21. By sequencing 13 individual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.