Article
An SNP map of human chromosome 22.
Nature - 28 Sept 2000
Mullikin J C, Hunt S E, Cole C G, Mortimore B J, Rice C M, Burton J, Matthews L H, Pavitt R, Plumb R W, Sims S K, Ainscough R M, Attwood J, Bailey J M, Barlow K, Bruskiewich R M, Butcher P N, Carter N P, Chen Y, Clee C M, Coggill P C, Davies J, Davies R M, Dawson E, Francis M D, Joy A A, Lamble R G, Langford C F, Macarthy J, Mall V, Moreland A, Overton-Larty E K, Ross M T, Smith L C, Steward C A, Sulston J E, Tinsley E J, Turney K J, Willey D L, Wilson G D, McMurray A A, Dunham I, Rogers J, Bentley D R
Abstract excerpt
The human genome sequence will provide a reference for measuring DNA sequence variation in human populations. Sequence variants are responsible for the genetic component of individuality, including complex characteristics such as disease susceptibility and drug response. Most sequence variants are single nucleotide polymorphisms (SNPs), where two alternate bases occur at one position. Comparison of any two...
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