Article
Cdc42 regulates multiple membrane traffic events in fission yeast.
Traffic (Copenhagen, Denmark) - 1 Dec 2011
Estravís Miguel, Rincón Sergio A, Santos Beatriz, Pérez Pilar
Abstract excerpt
Fission yeast Cdc42 regulates polarized growth and is involved in For3 formin activation and actin cable assembly. We show here that a thermosensitive strain carrying the cdc42L160S allele has membrane traffic defects independent of the actin cable defects. This strain has decreased acid phosphatase (AP) secretion, intracellular accumulation of vesicles and fragmentation of vacuoles. In addition, the exocyst is...
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