Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth.

Eukaryotic cell - 1 Jun 2002

Richman Tamara J, Sawyer Mathew M, Johnson Douglas I

Abstract excerpt

The Cdc42p GTPase controls polarized growth and cell cycle progression in eukaryotes from yeasts to mammals, and its precise subcellular localization is essential for its function. To examine the cell cycle-specific targeting of Cdc42p in living yeast cells, a green fluorescent protein (GFP)-Cdc42 fusion protein was used. In contrast to previous immunolocalization data, GFP-Cdc42p was found at the plasma membrane...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actomyosin
Share to cdc42 GTP-Binding Protein, Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Membrane

Share to Cell Polarity

Share to Green Fluorescent Proteins

Share to Intracellular Membranes

Share to Luminescent Proteins

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12455994
DOI: 10.1128/EC.1.3.458-468.2002
PMCID: PMC118019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth.PMID 12455994Read ↗

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.Semantic proximity Read ↗

CDC42 is required for polarized growth in human pathogen Candida albicans.Semantic proximity Read ↗

Regulation of Gic2 localization and function by phosphatidylinositol 4,5-bisphosphate during the establishment of cell polarity in budding yeast.Semantic proximity Read ↗

Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Cdc42p GTPase is involved in a G2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast.Semantic proximity Read ↗

Cdc42 promotes Bgs1 recruitment for septum synthesis and glucanase localization for cell separation during cytokinesis in fission yeast.Semantic proximity Read ↗

Transbilayer phospholipid flipping regulates Cdc42p signaling during polarized cell growth via Rga GTPase-activating proteins.Semantic proximity Read ↗

Distinct Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe.Semantic proximity Read ↗

Opposing roles for actin in Cdc42p polarization.Semantic proximity Read ↗

Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling.Semantic proximity Read ↗

Saccharomyces cerevisiae cdc42p GTPase is involved in preventing the recurrence of bud emergence during the cell cycle.Semantic proximity Read ↗

Exo-endocytic trafficking and the septin-based diffusion barrier are required for the maintenance of Cdc42p polarization during budding yeast asymmetric growth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.