Article
HER2 as a prognostic factor in breast cancer.
Oncology - 1 Jan 2001
Ménard S, Fortis S, Castiglioni F, Agresti R, Balsari A
Abstract excerpt
HER2 amplification/overexpression is a marker of poor prognosis in breast cancer. The prognostic impact of HER2 positivity is lower in node-negative compared with node-positive women. The only significant, independent prognostic factors in breast cancer are node status, HER2 status and menopausal status. HER2-positive tumors also contain p53 abnormalities, tend to be hormone receptor and bcl-2 negative, have...
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