Article
Issues and updates: evaluating estrogen receptor-alpha, progesterone receptor, and HER2 in breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2010
Allred D Craig
Abstract excerpt
There are currently three prognostic/predictive biomarkers used in routine clinical management of patients with breast cancer, and their assessment is mandatory. They include estrogen receptor-alpha (ERalpha), progesterone receptor (PgR), and the HER2 oncogene/oncoprotein. This paper briefly reviews the assessment of ERalpha, PgR, and HER2 in breast cancer, emphasizing recent progress and persistent controversies.
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