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The Role of ERBB2/HER2 Tyrosine Kinase Receptor in the Regulation of Cell Death

1 Oct 2020

Abstract excerpt

HER2 (Human Epidermal Growth Factor Receptor 2), also known as ERBB2, CD340, and Neu protooncogene, is a member of the epidermal growth factor receptor (EGRF) family. Members of the ERBB family, including HER2, activate molecular cascades that stimulate proliferation and migration of cancer cells, as well as their resistance to the anticancer therapy. These proteins are often overexpressed and/or mutated in...

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PMID: 33202212
DOI: 10.1134/s0006297920100156

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