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Article

The Distinctive Nature of HER2-Positive Breast Cancers

20 Oct 2005

Abstract excerpt

Breast cancer is not a single disease but a group of several important tumor subtypes, each with a different natural history and each requiring a different treatment. Overexpression of HER2 (which derives its name from human epidermal growth factor receptor 2) defines one of these unique subtypes. The HER2/neu gene is a member of a family of genes encoding transmembrane receptors for growth factors, including the...

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Identifiers

PMID: 16236735
DOI: 10.1056/nejmp058197

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