Article
Breast cancer molecular class ERBB2: preponderance of tumors with apocrine differentiation and expression of basal phenotype markers CK5, CK5/6, and EGFR.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Mar 2010
Bhargava Rohit, Beriwal Sushil, Striebel Joan M, Dabbs David J
Abstract excerpt
This is a study of 205 consecutive invasive breast carcinomas. The principal aim was to identify morphologic and immunohistochemical features of tumors that belong to the molecular class ERBB2. The invasive breast carcinomas were classified using semiquantitative immunohistochemical results for e...
Topics
- Apocrine Glands
- Biomarkers, Tumor
- Breast Neoplasms
- Carcinoma
- Carcinoma, Basal Cell
- Cell Differentiation
- ErbB Receptors
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Keratin-5
- Keratin-6
- Lymphocytes, Tumor-Infiltrating
- Phenotype
- Receptor, ErbB-2