Article
Contribution of prothrombin 20210A allele and factor V Leiden mutation to thrombosis risk in thrombophilic families with other hemostatic deficiencies.
Haematologica - 1 Nov 2001
Tirado I, Mateo J, Soria J M, Oliver A, Borrell M, Coll I, Vallvé C, Souto J C, Martínez-Sánchez E, Fontcuberta J
Abstract excerpt
BACKGROUND AND OBJECTIVES: The aims of this study were to compare the lifetime probability of developing thrombosis in 722 relatives of 132 thrombophilic families of symptomatic probands with recognized thrombophilic defects and to determine the prevalence of the factor V Leiden (FVL) mutation and the 20210A allele of the prothrombin gene (PT20210A) in these families. DESIGN AND METHODS: The study included 722...
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