Article
Clinical and analytical relevance of the combination of prothrombin 20210A/A and factor V Leiden: results from a large family.
British journal of haematology - 1 May 1999
Corral J, Zuazu-Jausoro I, Rivera J, González-Conejero R, Ferrer F, Vicente V
Abstract excerpt
We analysed the clinical and analytical features of 18 subjects from a Spanish family who bear several combinations of two prothrombotic mutations, factor V Leiden (FVL) and prothrombin 20210A. We identified three subjects homozygous for the 20210A prothrombin mutation which additionally were heterozygous for FVL. The combination of both mutations increases the risk of developing venous thrombotic episodes at the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
