Article
Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia.
Thrombosis and haemostasis - 1 Dec 1997
Makris M, Preston F E, Beauchamp N J, Cooper P C, Daly M E, Hampton K K, Bayliss P, Peake I R, Miller G J
Abstract excerpt
The presence of the 20210A allele of the prothrombin (PT) gene has recently been shown to be a risk factor for venous thromboembolism. This is probably mediated through increased plasma prothrombin levels. The aim of this study was to compare the prevalence of the prothrombin 20210A allele in control subjects and in subjects with recognised thrombophilia and to establish whether the additional inheritance of the...
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