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Article

The prothrombin 20210 G to A variation and thrombosis.

Current opinion in hematology - 1 Sept 1998

Bertina R M

Abstract excerpt

The 20210 G to A variation in the prothrombin gene was first described in 1996 and found to be associated with both elevated plasma prothrombin levels and a moderately increased risk for first venous thrombotic events. These findings generally have been confirmed in several independent studies. The 20210A allele seems to be rather common in white subpopulations, among whom the prevalence of heterozygous carriers...

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PMID: 9776213
DOI: 10.1097/00062752-199809000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The prothrombin 20210 G to A variation and thrombosis.PMID 9776213Read ↗

Prothrombin and the prothrombin 20210 G to A polymorphism: their relationship with hypercoagulability and thrombosis.Semantic proximity Read ↗

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The prothrombin gene variant 20210A in venous and arterial thromboembolism.Semantic proximity Read ↗

The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.Semantic proximity Read ↗

A homozygosity state for 20210A prothrombin variant in a young woman as cause of a deep venous thrombosis during pregnancy.Semantic proximity Read ↗

[20210A mutation of the prothrombin and venous thromboembolism gene].Semantic proximity Read ↗

Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease.Semantic proximity Read ↗

The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease.Semantic proximity Read ↗

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.Semantic proximity Read ↗

The 20210 G → A mutation in the 3′‐untranslated region of the prothrombin gene and the risk for arterial thrombotic diseaseSemantic proximity Read ↗

Prevalence of 20210 A allele of the prothrombin gene in venous thromboembolism patients.Semantic proximity Read ↗

Homozygotes for prothrombin gene 20210 A allele in a thrombophilic family without clinical manifestations of venous thromboembolism.Semantic proximity Read ↗

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