Article
The prothrombin gene G20210A variant in an unselected thromboembolic population. A Belgian prospective clinical study.
Acta clinica Belgica - 1 Oct 1998
Hainaut P, Gala J L, Lesage V, Lavenne E, Azerad M A, Zech F, Heusterspreute M, Philippe M, Moriau M
Abstract excerpt
The presence of the 20210A allele of the prothrombin gene has recently been shown to be a risk factor of venous thromboembolism, probably mediated through increased prothrombin levels. The aim of the study was to determine the frequency of the prothrombin 20210A allele in 193 consecutive unselect...
Topics
- Adult
- Age of Onset
- Alleles
- Belgium
- Cohort Studies
- Factor V
- Female
- Gene Frequency
- Heterozygote
- Humans
- Male
- Middle Aged
- Mutation