Article
The first homozygous family for prothrombin G20210A polymorphism reported in Latin America.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Feb 2009
Roman-Gonzalez Alejandro, Cardona Henry, Cardona-Maya Walter, Alvarez Leonor, Castaneda Serguei, Martinez Juliana, Torres Jose D, Tobon Luis, Bedoya Gabriel, Cadavid Angela
Abstract excerpt
The 20210A allele of the prothrombin gene is associated with increased risk of venous thromboembolism. In this study, we described manifestations of thrombosis in four generations of a Colombian family, with four 20210A homozygous carriers and six 20210G/A heterozygous carriers for polymorphism as well as unrelated participants from the same population. The levels of prothrombin in the 20210A homozygote patients...
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