Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The A20210 allele in the prothrombin gene enhances the risk of venous thrombosis in carriers of inherited protein S deficiency.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2000

Castaman G, Tosetto A, Cappellari A, Ruggeri M, Rodeghiero F

Abstract excerpt

Sixteen families with inherited protein S deficiency and venous thromboembolism (VT) were screened for the presence of factor V (FV) Leiden mutation and for the G20210A allele in the prothrombin gene. While FV Leiden was not detected in any of the families, protein S deficiency and prothrombin mutation were present in five families. To assess the risk of VT in carriers of the combined defects, a total of 92...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Heterozygote

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Protein S Deficiency

Share to Prothrombin

Share to Venous Thrombosis

Source

Identifiers

PMID: 10847418
DOI: 10.1097/00001721-200006000-00002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The A20210 allele in the prothrombin gene enhances the risk of venous thrombosis in carriers of inherited protein S deficiency.PMID 10847418Read ↗

Contribution of prothrombin 20210A allele and factor V Leiden mutation to thrombosis risk in thrombophilic families with other hemostatic deficiencies.Semantic proximity Read ↗

The risk of venous thromboembolism in family members with mutations in the genes of factor V or prothrombin or both.Semantic proximity Read ↗

Increased risk for venous thrombosis in carriers of the prothrombin G-->A20210 gene variant.Semantic proximity Read ↗

Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia.Semantic proximity Read ↗

Prothrombin G20210A Gene Mutation and Further Prothrombotic Risk Factors in Childhood ThrombophiliaSemantic proximity Read ↗

The prothrombin gene variant 20210A in venous and arterial thromboembolism.Semantic proximity Read ↗

Protein S type III deficiency is no risk factor for venous and arterial thromboembolism in 168 thrombophilic families: a retrospective study.Semantic proximity Read ↗

The prothrombin 20210 G to A variation and thrombosis.Semantic proximity Read ↗

Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives.Semantic proximity Read ↗

Impact of the factor II: G20210A variant on the risk of venous thromboembolism in relatives from families with the factor V: R506Q mutation.Semantic proximity Read ↗

Venous thrombosis with both heterozygous factor V Leiden (R507Q) and factor II (G20210A) mutations.Semantic proximity Read ↗

[20210A mutation of the prothrombin and venous thromboembolism gene].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.