The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.

Article

The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.

Thrombosis and haemostasis - 1 Sept 1998

Souto J C, Coll I, Llobet D, del Río E, Oliver A, Mateo J, Borrell M, Fontcuberta J

Abstract excerpt

We investigated the prevalence of the new recently reported mutation in the prothrombin gene (20210 A) in a sample of 116 unrelated patients with venous thromboembolism. We found 20 heterozygous carriers (17.2%, CI 95% 10.4-21.1). In comparison, we observed 13 carriers among 201 healthy unmatched...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Female
Genetic Markers
Humans
Male
Middle Aged
Mutation
Prevalence
Prothrombin
Spain
Venous Thrombosis

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