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Article

The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.

Thrombosis and haemostasis - 1 Sept 1998

Souto J C, Coll I, Llobet D, del Río E, Oliver A, Mateo J, Borrell M, Fontcuberta J

Abstract excerpt

We investigated the prevalence of the new recently reported mutation in the prothrombin gene (20210 A) in a sample of 116 unrelated patients with venous thromboembolism. We found 20 heterozygous carriers (17.2%, CI 95% 10.4-21.1). In comparison, we observed 13 carriers among 201 healthy unmatched controls (6.5%, CI 3.5-10.8). The 20210 A mutation seems to increase the risk of venous thrombosis 3-fold (odds ratio...

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PMID: 9759610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.PMID 9759610Read ↗

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The prothrombin gene G20210A variant in an unselected thromboembolic population. A Belgian prospective clinical study.Semantic proximity Read ↗

The prothrombin gene variant 20210A in venous and arterial thromboembolism.Semantic proximity Read ↗

Prevalence of 20210 A allele of the prothrombin gene in venous thromboembolism patients.Semantic proximity Read ↗

The 20210 A allele of the prothrombin gene is a common risk factor among Swedish outpatients with verified deep venous thrombosis.Semantic proximity Read ↗

The first homozygous family for prothrombin G20210A polymorphism reported in Latin America.Semantic proximity Read ↗

The prothrombin 20210 G to A variation and thrombosis.Semantic proximity Read ↗

Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease.Semantic proximity Read ↗

[Prevalence of G20210A prothrombin gene mutation in Poland].Semantic proximity Read ↗

Coexistence of three genetic risk factors in a Spanish thrombophilic family: Factor V Leiden, prothrombin 20210 and a new type I antithrombin deficiency.Semantic proximity Read ↗

The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease.Semantic proximity Read ↗

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.Semantic proximity Read ↗

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