Article
Factor analysis of asthma and atopy traits shows 2 major components, one of which is linked to markers on chromosome 5q.
The Journal of allergy and clinical immunology - 1 Nov 2001
Holberg C J, Halonen M, Solomon S, Graves P E, Baldini M, Erickson R P, Martinez F D
Abstract excerpt
BACKGROUND: A variety of definitions of asthma and atopy traits have been used in genetic studies. The variables used may be correlated, increasing the likelihood of type I error. OBJECTIVE: We sought to clarify and quantify phenotypes that may be characterized by related traits. Principal components and factor analysis were applied to the correlation matrix of asthma and atopy traits before linkage analysis....
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