Article
Variance components analyses of multiple asthma traits in a large sample of Australian families ascertained through a twin proband.
Allergy - 1 Feb 2006
Ferreira M A R, O'Gorman L, Le Souëf P, Burton P R, Toelle B G, Robertson C F, Martin N G, Duffy D L
Abstract excerpt
BACKGROUND: Intermediate phenotypes are often measured as a proxy for asthma. It is largely unclear to what extent the same set of environmental or genetic factors regulate these traits. OBJECTIVE: Estimate the environmental and genetic correlations between self-reported and clinical asthma traits. METHODS: A total of 3,073 subjects from 802 families were ascertained through a twin proband. Traits measured...
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