Article
High-throughput variation detection and genotyping using microarrays.
Genome research - 1 Nov 2001
Cutler D J, Zwick M E, Carrasquillo M M, Yohn C T, Tobin K P, Kashuk C, Mathews D J, Shah N A, Eichler E E, Warrington J A, Chakravarti A
Abstract excerpt
The genetic dissection of complex traits may ultimately require a large number of SNPs to be genotyped in multiple individuals who exhibit phenotypic variation in a trait of interest. Microarray technology can enable rapid genotyping of variation specific to study samples. To facilitate their use, we have developed an automated statistical method (ABACUS) to analyze microarray hybridization data and applied this...
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