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Article

Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation.

Genome research - 1 Aug 2001

Dong S, Wang E, Hsie L, Cao Y, Chen X, Gingeras T R

Abstract excerpt

A method for identifying and validating single nucleotide polymorphisms (SNPs) with high-density oligonucleotide arrays without the need for locus-specific polymerase chain reactions (PCR) is described in this report. Genomic DNAs were divided into subsets with complexity of ~10 Mb by restriction enzyme digestion and gel-based fragment size resolution, ligated to a common adaptor, and amplified with one primer in...

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Identifiers

PMID: 11483583
DOI: 10.1101/gr.171101
PMCID: PMC311102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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