Article
Simultaneous detection of multiple single-nucleotide polymorphisms by a simple membrane chip.
Genetic testing and molecular biomarkers - 1 Oct 2010
Yang Yu-Hsiang, Li Ruei-Nian, Tzou Shey-Cherng, Wang Jaw-Yuan, Lee Hsin-Pai, Wang Hsien-Chung, Chen Fang-Ming, Wang Yung-Hsin, Hsieh Ming-Chia, Huang Ming-Yii, Tseng Wei-Lung, Lin Shiu-Ru, Cheng Tian-Lu
Abstract excerpt
Technologies that screen multiple single-nucleotide polymorphisms (SNPs) could be very valuable in predicting patients' susceptibilities to diseases or responses to therapeutic interventions. In this study, we developed a chip that can accurately detect four SNPs at same time. This chip is cost-effective and user-friendly because it uses a detection protocol analogous to dot blotting and does not require...
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