Article
A genome-wide scalable SNP genotyping assay using microarray technology.
Nature genetics - 1 May 2005
Gunderson Kevin L, Steemers Frank J, Lee Grace, Mendoza Leo G, Chee Mark S
Abstract excerpt
Oligonucleotide probe arrays have enabled massively parallel analysis of gene expression levels from a single cDNA sample. Application of microarray technology to analyzing genomic DNA has been stymied by the sequence complexity of the entire human genome. A robust, single base-resolution direct genomic assay would extend the reach of microarray technology. We developed an array-based whole-genome genotyping...
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