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Article

Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis.

Brain research. Molecular brain research - 1 Nov 2001

Elliott J L

Abstract excerpt

Although pronounced changes in astrocytes and microglia accompany the neuronal degeneration observed in a murine model of familial amyotrophic lateral sclerosis, the significance of non-neuronal cell contribution to the disease process remains unclear. Activated astrocytes and microglia are capable of secreting numerous cytokines, some of which may have potentially harmful effects on neuron survival. For this...

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Source

Identifiers

PMID: 11687290
DOI: 10.1016/s0169-328x(01)00242-x

Genes

SOD1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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