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Article

A general mechanism for viral resistance to suicide gene expression.

Journal of molecular evolution - 1 Jul 2001

Bull J J, Badgett M R, Molineux I J

Abstract excerpt

Bacteriophage T7 was challenged with either of two toxic genes expressed from plasmids. Each plasmid contained a different gene downstream of a T7 promoter; cells harboring each plasmid caused an infection by wild-type T7 to abort. T7 evolved resistance to both inhibitors by avoidance of the plasmid expression system rather than by blocking or bypassing the effects of the specific toxic gene product. Resistance...

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Identifiers

PMID: 11683322
DOI: 10.1007/s002390010191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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