Article
Gene order constrains adaptation in bacteriophage T7.
Virology - 10 Oct 2005
Springman R, Badgett M R, Molineux I J, Bull J J
Abstract excerpt
The order of genes in the genome is commonly thought to have functional significance for gene regulation and fitness but has not heretofore been tested experimentally. We adapted a bacteriophage T7 variant harboring an ectopically positioned RNA polymerase gene to determine whether it could regai...
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