Article
Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.
PLoS genetics - 1 Jan 2012
Blower Tim R, Evans Terry J, Przybilski Rita, Fineran Peter C, Salmond George P C
Abstract excerpt
Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin system, ToxIN. A flagellum-dependent bacteriophage of the Myoviridae, ΦTE, evolved rare mutants that "escaped" ToxIN-mediated abortive infection within...
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