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Article

Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease.

Clinical endocrinology - 1 Oct 2001

Hunt P J, Marshall S E, Weetman A P, Bunce M, Bell J I, Wass J A, Welsh K I

Abstract excerpt

OBJECTIVES: Associations between autoimmune thyroid disease and antigens of the major histocompatibility complex (MHC) have long been recognized. Graves' disease (GD) is associated with the histocompatibility leucocyte antigen (HLA) haplotype A*01-B*0801-DRB1*0301-DQA1*0501-DQB1*0201 (or B8/DR3) whereas autoimmune hypothyroidism (AIH) has been weakly associated with HLA DRB1*03, *04 and *11/*12 alleles (or DR3,...

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Source

Identifiers

PMID: 11678832
DOI: 10.1046/j.1365-2265.2001.01356.x

Genes

TNF
TAP1
TAP2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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