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Article

Association analysis of interleukin gene polymorphisms in autoimmune thyroid diseases in the Tunisian population.

European cytokine network - 1 Dec 2007

Kammoun-Krichen Maha, Bougacha-Elleuch Noura, Makni Kaouthar, Rebai Maha, Peraldi-Roux Sylvie, Rebai Ahmed, Mnif Mouna, Abid Mohamed, Jouida Joumaa, Ayadi Hammadi

Abstract excerpt

Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and autoimmune hypothyroidism (AH), are inherited as complex traits. Among the genes contributing to AITDs susceptibility are genes of the IL-1 family. IL-1 regulates T and B lymphocyte maturation, including the induction of several cytokines and cytokine receptors. Therefore, disturbances of this balance may not only play a role in inflammation...

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Identifiers

PMID: 17964974
DOI: 10.1684/ecn.2007.0104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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