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Article

Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease.

Genes and immunity - 1 Jun 2008

Zeitlin A A, Heward J M, Newby P R, Carr-Smith J D, Franklyn J A, Gough S C L, Simmonds M J

Abstract excerpt

Graves' disease (GD) and Hashimoto's thyroiditis (HT) represent the commonest forms of autoimmune thyroid disease (AITD) each presenting with distinct clinical features. Progress has been made in determining association of HLA class II DRB1, DQB1 and DQA1 loci with GD demonstrating a predisposing effect for DR3 (DRB1(*)03-DQB1(*)02-DQA1(*)05) and a protective effect for DR7 (DRB1(*)07-DQB1(*)02-DQA1(*)02). Small...

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PMID: 18449200
DOI: 10.1038/gene.2008.26

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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