Article
Immunoregulatory and susceptibility genes in thyroid and polyglandular autoimmunity.
Thyroid : official journal of the American Thyroid Association - 1 Mar 2005
Dittmar Manuela, Kahaly George J
Abstract excerpt
The etiology of autoimmune thyroid diseases (AITD) is based on genetic and nongenetic factors. Genome-wide screening and linkage analyses have identified several chromosomal regions that are linked to AITD. These are HT-1 (on chromosome 13q33) and HT-2 (chromosome 12q22) for Hashimoto's thyroiditis (HT), and GD-1 (chromosome 14q31), GD-2 (chromosome 20q11.2), and GD-3 (chromosome Xq21) for Graves' disease (GD)....
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