Article
p53 analysis in gallbladder cancer: comparison of gene analysis versus immunohistochemistry.
Anticancer research - 1 Jan 2000
Puhalla H, Kandioler D, Ludwig C, Filipits M, Wrba F, Laengle F, Jakesz R, Gruenberger T
Abstract excerpt
BACKGROUND: The survival of gallbladder cancer (GC) patients is generally poor. Both after resection and palliative procedures, additive therapy is often administered to increase outcome. The effect of cytotoxic therapies depends on a functioning p53 gene. The aim of this study was to investigate whether p53 immunohistochemistry (IHC) or p53 gene sequencing are of any survival influence in GC. PATIENTS AND...
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