Article
[The acetylator polymorphism in a Khmer population: clinical consequences].
Therapie - 1 Jan 2000
Bechtel Y C, Bechtel P R, Lelouët H, Choisy H, Dy N R
Abstract excerpt
The great variability of slow acetylator (SA) and/or rapid acetylator (RA) frequency is mainly due to ethnic-racial origin. Using the urinary elimination ratio of three metabolites of caffeine--acetylamino formylamino methyluracil (AFMU) to AFMU + 1-methyl urate (1U) + 1-methyl xanthine (1X)--we settled the acetylation phenotype in 54 independent subjects of Khmer and 70 independent subjects of Caucasian origin....
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