Article
[Comparative analysis of N-acetylation polymorphism in humans as determined by phenotyping and genotyping].
Genetika - 1 Aug 2006
Goldenkova-Pavlova I V, Bruskin S A, Abdeev R M, Markarova E V, Bigvava S G, Radkevich L A, Kozhekbaeva Zh M, Glotov A S, Gra O A, Zasedatelev A S, Nasedkina T V, Kurdanov Kh A, Piruzian E S
Abstract excerpt
The N-acetylation polymorphisms of volunteers from the Moscow population analyzed by phenotyping and genotyping have been compared. The ratios between the proportions of fast acetylators (FAs) and slow acetylators (SAs) estimated by phenotyping and genotyping do not differ significantly from each other (47 and 44%, respectively). The absolute acetylation rate widely varies in both FAs and SAs. The NAT2 genotype...
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