Article
Acetylator phenotyping in patients with malignant lymphomas, using caffeine as the metabolic probe.
Polish journal of pharmacology - 1 Jan 2000
William Basem M, Abdel-tawab Ahmed M, Hassan Essam A, Mohamed Omar Fathy
Abstract excerpt
OBJECTIVE: The study was designed to answer the question whether a particular (slow/fast) acetylator phenotype is a risk for malignant lymphoma patients. Differences in acetylator phenotypes were previously described in urinary bladder and colorectal carcinoma patients compared to controls. Addressing this issue may help understanding the possible role of xenobiotics' metabolism in the pathogenesis of malignant...
Topics
- Acetylation
- Acetyltransferases
- Adolescent
- Adult
- Aged
- Caffeine
- Child
- Female
- Humans
- Inactivation, Metabolic
- Lymphoma
- Male
- Middle Aged
- Phenotype
- Time Factors
