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Article

An assessment of acetylator polymorphism and its relevance in Papua New Guinea.

Papua and New Guinea medical journal - 1 Jun 1990

Hombhanje F

Abstract excerpt

A number of clinically useful drugs such as isoniazid, sulphonamides, procainamide and dapsone are rapidly inactivated and eliminated metabolically by an acetyltransferase enzyme. The rate of elimination of these drugs is dependent upon the level of enzymatic activity, which is known to be genetically determined and exhibits ethnic and geographical variation. The study of acetylation polymorphism therefore is...

Topics

Acetylation
Acetyltransferases
Adult
Female
Humans
Male
New Guinea
Phenotype
Polymorphism, Genetic
Racial Groups
Sulfamethazine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 2238823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2238823-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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