Article
Role of Id proteins in embryonic and tumor angiogenesis.
Trends in cardiovascular medicine - 1 Aug 2001
Benezra R
Abstract excerpt
It has been shown recently in mouse model systems that the Id proteins play a critical role in angiogenesis both during embryogenesis and tumor formation. The Id proteins are intracellular proteins that inhibit the activity of differentiation-promoting transcription factors and thereby block differentiation and promote cell cycle progression. Loss of Id function in mice leads to premature neural differentiation...
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