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Article

Id proteins in the vasculature: from molecular biology to cardiopulmonary medicine

1 Oct 2014

Abstract excerpt

The inhibitors of differentiation (Id) proteins belong to the helix-loop-helix group of transcription factors and regulate cell differentiation and proliferation. Recent studies have reported that Id proteins play important roles in cardiogenesis and formation of the vasculature. We have also demonstrated that heritable pulmonary arterial hypertension (HPAH) patients have dysregulated Id gene expression in...

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PMID: 25274246
DOI: 10.1093/cvr/cvu215

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